Summary: The SARS-CoV-2 papain-like protease (PLpro) is a target for antiviral drug development. It is essential for processing viral polyproteins for replication and functions in host immune evasion by cleaving ubiquitin (Ub) and ubiquitin-like protein (Ubl) conjugates. While highly conserved. SARS-CoV-2 and SARS-CoV PLpro have contrasting Ub/Ubl substrate preferences. https://www.chiggate.com/replica-beach-walk-candle-fashion/