Pentobarbital will lessen the level or impact of ramelteon by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Significance Unfamiliar. pentobarbital will lower the extent or impact of tofacitinib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. Lack of, or diminished reaction to tofacitinib might come about when coadministered with ... https://what-type-of-drug-is-nemb76430.ampedpages.com/the-2-minute-rule-for-what-kind-of-drug-is-nembutal-58185474